Searchable abstracts of presentations at key conferences in endocrinology

ea0029p283 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012

Development of primary hyperparathyroidism is closely associated with the onset of dyslipidemia and insulin resistance in a large family harboring a MEN1 gene mutation

Anselmo J. , Moniz C. , Sousa I. , Cesar R.

Introduction: Dyslipidemia is a common finding in patients with primary hyperparathyroidism and together with hypertension and glucose intolerance seems to be responsible by the increased risk of cardiovascular disease in hyperparathyroid patients. In the present work we studied members of a family harboring a MEN1 gene mutation (type 1 multiple endocrine neoplasia syndrome). The penetrance of primary hyperparathyroidism in this condition is close to 100%, starting usually dur...